Ozone Or Peroxide Patents (Class 436/135)
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Patent number: 11313803Abstract: An OH radical detection probe (102) includes an aromatic carboxylic acid, a polar aprotic organic solvent, and a polar protic organic solvent.Type: GrantFiled: August 20, 2019Date of Patent: April 26, 2022Assignee: IHI CORPORATIONInventors: Takao Kurata, Katsumi Takahashi, Kazuyuki Sakamoto
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Patent number: 11100357Abstract: A first image may be received by a processor. The processor may identify an image quality measure of which to evaluate the first image. The processor may compare the first image to one or more images. The processor may generate a first image quality score for the first image based on the comparing. The processor may convert the first image quality score into a first micro air-quality index. The processor may transmit the first micro air-quality index to a recording device. Additionally, a recording device may capture a first image. The recording device may send the first image to a database that may include a model associated with an image quality measure. The recording device may receive a first micro air-quality index associated with the image quality measure. The recording device may rearrange a display of the first image to display the first micro air-quality index.Type: GrantFiled: July 16, 2019Date of Patent: August 24, 2021Assignee: International Business Machines CorporationInventors: Fang Wang, Su Liu, Kevin Shank, Cheng Xu
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Patent number: 9222884Abstract: Provided is a hydrogen peroxide sensitive metal nanoparticle including: a metal nanoparticle including a biocompatible metal and a hydrogen peroxide reactive ion which is bonded to a surface of the metal nanoparticle and is oxidized by hydrogen peroxide.Type: GrantFiled: August 30, 2013Date of Patent: December 29, 2015Assignees: SAMSUNG ELECTRONICS CO., LTD., POSTECH ACADEMY-INDUSTRY FOUNDATIONInventors: Kyu-hyun Im, No-kyoung Park, Jae-hyun Hur, Sung-jee Kim, Ju-taek Nam, Seong-ho Park, Sang-hwa Jeong
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Patent number: 9027385Abstract: A method of measuring density of a sterilant aerosol e.g. aqueous hydrogen peroxide, in a gas stream (such as a stream of air) for the purposes of measuring sterilant dosage comprising: passing a gas stream at flow rate past an electrically heated element and measuring a first cooling effect, passing an aerosol suspended in a gas stream at flow rate past an electrically heated element and measuring a second cooling effect and measuring the difference between the first cooling effect and second cooling effect and correlating the difference with aerosol density. The total dosage can thus be determined. A measured dosage of a sterilant aerosol can be delivered by way of a feedback loop to halt further delivery of sterilant aerosol when the amount of aerosol delivered reaches a predetermined dosage. The methods allow sterilization to be certified.Type: GrantFiled: June 30, 2009Date of Patent: May 12, 2015Assignee: Saban Ventures Pty LimitedInventors: Brian Hingley, Michael Potas
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Patent number: 9012230Abstract: The present disclosure relates to a sulfonated benzene compound emitting fluorescence by reaction with hydrogen peroxide, aqueous-dispersed fluorescent nanoprobes applicable for real-time detection of hydrogen peroxide, and a fluorescent nanoprobe fabrication method. The fluorescent nanoprobe contains the following sulfonated benzene compound and water.Type: GrantFiled: January 31, 2012Date of Patent: April 21, 2015Assignee: Korea Institute of Science and TechnologyInventors: Sehoon Kim, Ick Chan Kwon, Jai Kyeong Kim, Chang-Keun Lim, Jeongyun Heo
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Patent number: 9005524Abstract: The present invention provides a series of systems, devices, and methods relating to the determination of explosives, such as peroxides or peroxide precursors, and other species. Embodiments of the invention may allow a sample suspected of containing an explosive (e.g., a peroxide) or other species to interact with a reactant, wherein the sample may react and cause light emission from the reactant. Advantages of the present invention may include the simplification of devices for determination of peroxide-based explosives, wherein the devices are portable and, in some cases, disposable. Other advantages may include relative ease of fabrication and operation.Type: GrantFiled: July 9, 2010Date of Patent: April 14, 2015Assignee: Nomadics, Inc.Inventors: Robert Deans, Aimee Rose, Kevin M. Bardon, Lawrence F. Hancock, Timothy M. Swager
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Patent number: 8980636Abstract: A system and method for performing automated titrations. An automatic titrator utilizes control devices and sensors adapted for various chemical reactions to perform titrations and determine the content of a desired component of a solution. Batch and continuous mode titrations are possible. Titrant is added to a sample either in varying amounts or rates and a titration endpoint is observed via sensors. Control devices detect when the titration endpoint occurs and calculates the desired content. Various reactions within the solution may be suppressed in order to titrate isolated components individually.Type: GrantFiled: March 15, 2013Date of Patent: March 17, 2015Assignee: Ecolab USA Inc.Inventors: John Wilhelm Bolduc, Blake Roberts Otting, Paul R. Kraus, Robert Ryther
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Publication number: 20150072435Abstract: An apparatus and a method for the colorimetric detection testing of peroxide-based compositions is disclosed. The apparatus comprises a first carrier having an acidic compound in dry form for hydrolysis of peroxide-based compounds and a second carrier having a colorimetric detection reagent composition in dry form. The carriers are positioned with respect to a support member to facilitate transfer of a solution containing a peroxide-based compound hydrolyzed by the acidic compound when activated into contact with the reagent composition of the second carrier for observation of any resulting color indication. The method comprises steps of applying the acidic compound and colorimetric detection reagent composition is liquid forms to the respective carriers and allowing the applied formulations to dry.Type: ApplicationFiled: September 9, 2013Publication date: March 12, 2015Applicant: Precision Laboratories, Inc.Inventors: Eva Hrboticka, James A. Bertsch
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Publication number: 20150050745Abstract: An indicator for detecting peroxide can detect the peroxide through change of hue thereof by reacting the peroxide according to a predefined concentration and a predefined sterilization treatment condition thereof. The indicator has better resistance against weather or light and preservation stability than those of prior indicators including inorganic compounds or organic compounds as discoloration components, can clearly change an arbitrary hue thereof under suitable discoloration rate, and has visible distinguishability. The indicator for detecting peroxide includes powdery metal sulfide, that undergoes discoloration by reacting with the peroxide. In particular a discoloration layer including the metal sulfide is applied onto at least a portion of a base substrate.Type: ApplicationFiled: February 27, 2013Publication date: February 19, 2015Inventors: Ryo Karato, Nobuyuki Ando
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Patent number: 8940542Abstract: A sensor for detecting and/or quantifying the amount of analyte in a sample, the sensor including: a sensing region; and a barrier layer including a reactive oxygen species (ROS)-quenching, analyte-permeable membrane having an ROS-quenching agent adsorbed to the membrane; wherein the sensor is adapted so that the sample enters the sensing region of the sensor through the barrier layer.Type: GrantFiled: October 8, 2013Date of Patent: January 27, 2015Assignee: Lighthouse Medical LimitedInventors: William Paterson, Nick Barwell, Bruce Culbert, Barry Colin Crane
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Patent number: 8932871Abstract: A system for a vehicle includes a first ozone sensor that generates a first sensor signal indicating a first amount of ozone in air flowing into a radiator. A second ozone sensor generates a second sensor signal indicating a second amount of ozone in air flowing out of the radiator. A control module receives the first sensor signal and the second sensor signal and determines an ozone conversion rate based on the first sensor signal and the second sensor signal.Type: GrantFiled: November 8, 2011Date of Patent: January 13, 2015Inventors: Scott H. Wittkopp, Chang H. Kim, Brian T. Heil
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Publication number: 20150004710Abstract: Reagents and methods are disclosed for detection of oxidizers and inorganic salts and other analytes of interest. The reagents can interact with their target analytes, especially oxidizer compositions or oxidizer-based explosives, to selectively enhance their ionization yield, interacting by chemical reaction or by forming an associative adduct which facilitates their detection. For example, the reagents can adduct with the counter-ion of the intended analyte for improved direct detection and/or react chemically via acid-base reactions to produce a new product for detection. In another aspect of the invention, reactive reagents and methods are also disclosed that facilitate indirect detection of the analyte at lower temperatures based on reduction-oxidation (redox) chemistry. These reagents are particularly useful in detecting oxidizer analytes.Type: ApplicationFiled: July 23, 2013Publication date: January 1, 2015Applicant: Massachusetts Institute of TechnologyInventors: Kerin E. Gregory, Roderick R. Kunz, Michael Sworin
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Publication number: 20150005193Abstract: Disclosed herein are “equipment-free” flow-through assay devices based on patterned porous media, methods of making same, and methods of using same. The porous, hydrophilic media are patterned with hydrophobic barriers for performing assays on liquids.Type: ApplicationFiled: June 20, 2014Publication date: January 1, 2015Inventors: Scott Thomas Phillips, Gregory Gerald Lewis, Jessica Sloane Robbins
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Publication number: 20140369939Abstract: Injectable compositions for the MRI detection of an analyte selected from the group consisting of reactive oxygen species, proteases and enzymes, comprising a) a matrix material based on a responsive hydrophobic polymer capable of undergoing a chemical reaction with the analyte to be detected, such reaction leading to a disruption of the polymer chain of the responsive polymer, b) a contrast agent suitable for use in magnetic resonance imaging, embedded in or encapsulated in the polymer a), c) optionally, a functionality capable of binding a marker or probe or a probe for creating a second detection signal, and d) optionally, a non-responsive polymer not undergoing a chemical reaction with the analyte under the conditions where polymer a) undergoes a reaction leading to chain breakageType: ApplicationFiled: June 10, 2014Publication date: December 18, 2014Inventors: V. PRASAD SHASTRI, Pradeep P. Wyss
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Patent number: 8871522Abstract: The presence of hydrogen peroxide vapor is detected with high sensitivity. Oxygen molecules in the air are ionized by electrons generated by a discharge plasma, thereby producing an oxygen molecule negative ion O2?. The oxygen molecule negative ion O2? produced is supplied to a space in which a hydrogen peroxide molecule H2O2 is to be detected. If a hydrogen peroxide molecule H2O2 is present, a cluster ion O2?(H2O2) of the oxygen molecule negative ion O2? and hydrogen peroxide molecule H2O2 is produced. The hydrogen peroxide molecule H2O2, therefore, can be detected by mass spectrometry. Other gas-phase negative ions such as chloride ion Cl? can be used besides the oxygen molecule negative ion O2?.Type: GrantFiled: August 15, 2011Date of Patent: October 28, 2014Assignee: University of YamanashiInventor: Kenzo Hiraoka
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Publication number: 20140315323Abstract: The invention relates to the use of nanoparticles of at least one oxide of at least one transition metal doped with a rare earth element, particularly YxVO4Eu1-x nanoparticles obtained through a sol-gel process, as a sensitive material in a chemical sensor for detecting peroxide-compound vapors. The material is used in a liquid process, in a spray of the initial sol, or in a solid thin film after being deposited on a substrate. The inorganic, fluorescent character of the nanoparticles makes it possible to obtain a sensitive material for an optical sensor that has good performance stability over time. The intended uses are the detection of explosives or explosive precursors, particularly peroxides, the control or monitoring of atmospheric pollution and ambient-air quality, and the monitoring of industrial sites.Type: ApplicationFiled: September 28, 2012Publication date: October 23, 2014Applicant: COMMISSARIAT À L'ÉNERGIE ATOMIQUE ET AUX ÉNERGIES ALTERNATIVESInventors: Franck Pereira, Natacha Oudot
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Publication number: 20140255510Abstract: Peracid stable fluorescent active compounds in highly acidic, equilibrium peroxycarboxylic acid sanitizing compositions are disclosed as having improved fluorescent stability allowing for monitoring of peroxycarboxylic acid concentration by conductivity and/or optical sensors. Beneficially, the compositions are also low odor and low/no VOC dual functioning acid wash and sanitizing compositions.Type: ApplicationFiled: March 5, 2013Publication date: September 11, 2014Applicant: ECOLAB USA INC.Inventors: Junzhong Li, David D. McSherry, Allison Brewster, Richard Staub
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Publication number: 20140248218Abstract: Herein are provided, inter alia, compositions including boronic esters, which in the presence of H2O2, provide for the detection of ROS compounds such as endogenous H2O2 and methods of using the compositions to detect ROS compounds.Type: ApplicationFiled: February 7, 2014Publication date: September 4, 2014Applicant: The Regents of the University of CaliforniaInventors: Kevin B. Daniel, Seth M. Cohen, Jody L. Major Jourden
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Patent number: 8791258Abstract: The present invention provides a novel class of pro-fluorescent probes for reactive oxygen species (ROS). One exemplary probe is mitochondria peroxy yellow 1 (MitoPY1), a new type of flurophore for imaging mitochondrial H2O2 in living cells with ROS and spatial specificity. The invention also provides methods of using pro-fluorescent probes to detect analytes. One exemplary method comprises using a pro-fluorescent probe of the invention to detect an explosive.Type: GrantFiled: June 8, 2009Date of Patent: July 29, 2014Assignee: The Regents of the University of CaliforniaInventor: Christopher J. Chang
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Patent number: 8778271Abstract: Sensors for the detection of free radicals and free radical forming compounds including, for example, peroxides, as well as energetic radiation, UV light, plasma or heat each such sensor including a functional component are described herein. In addition, this disclosure includes methods for making such sensors and methods for using sensors including a functional component and devices incorporating such sensors.Type: GrantFiled: May 21, 2009Date of Patent: July 15, 2014Assignee: Triton Systems Inc.Inventors: John Lock, Edward Geraghty, Lawino Kagumba, Norm Rice, Keith Higginson, Ken Mahmud, Arthur Gavrin
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Publication number: 20140193923Abstract: Methods, compositions, and systems for detecting explosives is disclosed and described. A sensor for detecting explosives can comprise a porous hydrophilic material modified with a series of ? conjugated molecules with the general structure: [EW]-[CS]-[PED] wherein EW is an electron withdrawing group, CS is a conjugated system, and where PED is a pre-electron donating group. The porous hydrophilic material is capable of detecting hydrogen peroxide by reacting the aryl boronate group (or other Pre-ED groups) with the hydrogen peroxide to provide a fluorescent change.Type: ApplicationFiled: April 18, 2013Publication date: July 10, 2014Inventor: University of Utah Research Foundation
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Publication number: 20140179016Abstract: The present invention provides a reagent for measuring a degree of oxidative stress that includes a compound represented by the following general formula (I) or a salt thereof, and a method of measuring a degree of oxidative stress using the reagent for measuring a degree of oxidative stress. In the general formula (I), R1, R2, R3 and R4 each independently represent a hydrogen atom, an ethyl group, an isopropyl group, a hydroxyalkyl group that has 1 to 4 carbon atoms, or a phenyl group, and at least one of R1, R2, R3 or R4 represents an isopropyl group, a hydroxyalkyl group having 1 to 4 carbon atoms, or a phenyl group.Type: ApplicationFiled: December 22, 2013Publication date: June 26, 2014Applicant: ARKRAY, INC.Inventors: Kazuhiro Omiya, Toshihiro Imai, Emi Ashibe
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Patent number: 8748191Abstract: Analytical systems and methods are provided for simultaneously dispensing metered volumes of fluids at different rates and mixing the fluids to generate a mixed sample having the fluids in proportion to the different rates at which they were dispensed. In some cases two or more of the fluids are premixed prior to mixing with other fluids. In some cases a use composition and diluent are simultaneously dispensed at different rates and premixed to form a diluted sample. One or more reagents may be mixed with the diluted sample and the sample mixture can be analyzed to determine characteristics of the use composition.Type: GrantFiled: August 2, 2010Date of Patent: June 10, 2014Assignee: Ecolab USA Inc.Inventors: Paul R. Kraus, William M. Christensen
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Publication number: 20140154808Abstract: Compositions, devices and processes related to etching of a very thin layer or fine particles of a metal are disclosed for monitoring a variety of parameters, such as time, temperature, time-temperature, thawing, freezing, microwave, humidity, ionizing radiation, sterilization and chemicals. These devices have capabilities of producing a long and sharp induction period of an irreversible visual change. The devices are composed of an indicator comprising a very thin layer of a metal and an activator, e.g., a reactant, such as water, water vapor, an acid, a base, oxidizing agent or their precursors, which is capable of reacting with the said indicator. Ink formulations composed of a metal powder and a proper activator can be used for monitoring several sterilization processes, such as sterilization with steam. When water is used as an activator, a thin layer of metals, such as that of aluminum can be used as steam sterilization or humidity indicator.Type: ApplicationFiled: December 3, 2012Publication date: June 5, 2014Inventor: Gordhanbhai N. Patel
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Publication number: 20140127824Abstract: A method for the detection of explosives using a single sample. The explosives include nitro aliphatic and nitro aromatic-based explosives. The method includes steps which require different pHs to discriminate between these types of explosives and at least in the detection step of the nitro aliphatic explosive requires the presence of a nitro aromatic compound. A kit for detecting explosives which includes a medium for collecting a sample, a base optionally impregnated on the medium; and a nitro aromatic solution for detecting a nitro aliphatic explosive by contacting the solution with the sample on the medium. A reagent including a nitro aromatic compound, having one or more additional electron withdrawing groups, in the presence of a basic compound usable for detecting nitro aliphatic explosives.Type: ApplicationFiled: June 27, 2012Publication date: May 8, 2014Applicant: MISTRAL DETECTION LTD.Inventor: Shai Amisar
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Publication number: 20140065718Abstract: Provided is a hydrogen peroxide sensitive metal nanoparticle including: a metal nanoparticle including a biocompatible metal and a hydrogen peroxide reactive ion which is bonded to a surface of the metal nanoparticle and is oxidized by hydrogen peroxide.Type: ApplicationFiled: August 30, 2013Publication date: March 6, 2014Applicants: POSTECH ACADEMY-INDUSTRY FOUNDATION, Samsung Electronics Co., Ltd.Inventors: Kyu-hyun IM, No-kyoung PARK, Jae-hyun HUR, Sung-jee KIM, Ju-taek NAM, Seong-ho PARK, Sang-hwa JEONG
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Publication number: 20140057360Abstract: An arrangement for detecting hydrogen peroxide includes a sample space configured to receive a hydrogen-peroxide-containing gas. The sample space is fluidically connected to a hydrogen-peroxide-selective colorimetric detection reagent. The arrangement also includes at least one radiation source configured to irradiate the detection reagent and at least one detector configured to detect at least one optical property of the colorimetric detection reagent. This arrangement enables detection of hydrogen peroxide in the gaseous phase without the need to transfer hydrogen peroxide to the liquid phase. As a result, a simplified measurement behavior and additionally a highly sensitive measurement are attained.Type: ApplicationFiled: December 14, 2011Publication date: February 27, 2014Applicant: Robert Bosch GmbHInventors: Petra Neff, Markus Widenmeyer
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Patent number: 8637319Abstract: A method for detecting human or animal blood traces on a surface is described. The method is fundamentally based on the reaction of luminol and includes the preliminary operation of atomizing an inorganic powder suspension, such as titania, silica, alumina, hydroxyapatite, or the like, onto the surface to be investigated, after which a composition of luminol, a peroxidic oxidizing agent and an alkaline agent in an amount providing a pH within the range of 10 to 14, is atomized on the surface. A kit for carrying out the detection method of the invention is also described.Type: GrantFiled: December 2, 2009Date of Patent: January 28, 2014Assignee: Universita' Degli Studi di TorinoInventors: Gianmario Martra, Simone Priante, Marco Vincenti
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Publication number: 20130315829Abstract: The present disclosure provides compounds that detect reactive oxygen species in a living cell, in a multicellular organism, or in a cell-free sample. The compounds find use in a variety of applications, which are also provided. The present disclosure provides compositions comprising a subject compound.Type: ApplicationFiled: April 21, 2011Publication date: November 28, 2013Applicant: The Regents of the University of CaliforniaInventors: Christopher J. Chang, Genevieve C. van de Bittner, Elena A. Dubikovskaya, Carolyn R. Bertozzi
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Patent number: 8580515Abstract: A method for surface modification of single walled carbon nanotubes is described. In one embodiment, the method includes the steps of providing a detergent solution, adding a plurality of single walled carbon nanotubes into the detergent solution, performing a first sonication to disperse the single walled carbon nanotubes in the detergent solution, and performing a second sonication after the first sonication to make detergent encased single walled carbon nanotubes. At least one of the plurality of single walled carbon nanotubes is at least partially wrapped by one or more detergent molecules to make it a detergent encased single walled carbon nanotube. In one embodiment, the detergent comprises SDS, PSS or a combination of them. The surface modified carbon nanotubes can be used to detect a chemical compound by associating a solution of the surface modified nanotubes with the chemical compound and optically detecting a chemical property change of the solution.Type: GrantFiled: November 17, 2006Date of Patent: November 12, 2013Assignee: Board of Trustees of the University of ArkansasInventors: Wei Zhao, Chulho Song
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Patent number: 8563320Abstract: A use composition monitor determines the concentration of peracid and/or peroxide in a use composition using a kinetic assay procedure. A sample mixture containing a sample of the use composition, a diluent and at least one reagent is prepared and analyzed using, for example, an optical detector. A reduced-turbulence optical detector can be used to improve collected response data. A reduced-turbulence optical detector can include a cell body disposed about a length of transparent tubing. The cell body positions one or more emitter/receiver pairs about the transparent tubing. Thus, tube junctions are eliminated and sample flow within the tube is substantially turbulence free.Type: GrantFiled: February 15, 2012Date of Patent: October 22, 2013Assignee: Ecolab USA Inc.Inventors: Eugene Tokhtuev, Christopher Owen, Anna Pilipchenko, Paul Schilling, Daniel Kamben
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Publication number: 20130260471Abstract: The invention concerns the use of cyclic azaboronates as sensitive materials in sensors for the detection of the presence of peroxides, in particular hydrogen peroxide, in a gaseous environment. It further concerns new cyclic azaboronates, as well as sensors comprising these azaboronates as sensitive materials. Applications: Fight against terrorism, monitoring for security purposes of sites in which peroxides or peroxidable compounds are manufactured, stored, and/or used, monitoring of atmospheric pollution, etc.Type: ApplicationFiled: October 17, 2011Publication date: October 3, 2013Inventors: Thomas Caron, Myriam Bouhadid, Eric Pasquinet, Pierre Montmeat, Francoise Serein-Spirau
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Patent number: 8507288Abstract: The invention relates to the use of carbon nanomaterials as a filtration material pervious to nitrogen dioxide and impervious to ozone. The invention also relates to the use of carbon nanomaterials having a specific surface, measured by the BET method, of 15 to 40 m2/g inclusive and a form factor, equal to the ratio (highest dimension/lowest dimension) of the nanomaterial, of 5 to 250 inclusive, as material for filtering a gas mixture containing nitrogen dioxide and ozone, being pervious to the nitrogen dioxide and impervious to the ozone. The invention can be used in the field of air pollution.Type: GrantFiled: May 27, 2009Date of Patent: August 13, 2013Assignees: Centre National de la Recherche Scientifique, Universite Blaise Pascal—Clermont—Ferrand IIInventors: Alain Pauly, Marc Dubois, Katia Guerin, André Hamwi, Jérôme Brunet, Christelle Varenne, Bernard Lauron
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Patent number: 8497132Abstract: An ozone gas concentration measurement method that can easily measure the concentration of ozone gas. A process gas containing ozone gas is produced from a raw gas containing oxygen gas. The number of moles of gas molecules contained in the process gas is measured. The concentration of the ozone gas contained in the process gas is calculated based on the number of moles of gas molecules contained in the process gas.Type: GrantFiled: November 5, 2009Date of Patent: July 30, 2013Assignee: Tokyo Electron LimitedInventor: Takehiro Shindou
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Publication number: 20130130398Abstract: Methods, compositions, and systems for detecting explosives is disclosed and described. A sensor for detecting explosives can comprise a porous hydrophilic material modified with a titanium oxo compound having the following structure (I) where L is a ligand. Additionally, the porous hydrophilic material can be capable of detecting hydrogen peroxide vapor by complexing the titanium oxo compound and the hydrogen peroxide to provide a color change.Type: ApplicationFiled: November 19, 2010Publication date: May 23, 2013Applicant: University of UtahInventor: Ling Zang
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Patent number: 8431077Abstract: This invention concerns a hydrogen peroxide sterilization device, with injection of hydrogen peroxide vapor, provided with a vaporizer that feeds a sterilization chamber, with a dose that varies in function of the control performed by a computer or control unit. The vaporizer works with a pressure inferior to the atmospheric one and is heated by an electrical resistance heater, or by micro-waves. All the vaporization process is made in vacuum, by heat or ultra-sounds. The filling of the sterilant agent is made drop-by-drop by a capillary tube which transforms the liquid into a pulverized gas. The computer controls the electrical valve following the dosing pump from the pressure and/or temperature information that comes from various pressure and/or temperature sensors, whereby the pressure inside the chamber is maintained during the sterilization process in a constant predefined value, appropriate to use simple cellulose-base paper or paper composed to the packaging of the devices.Type: GrantFiled: July 10, 2007Date of Patent: April 30, 2013Inventor: Helder da Costa Goncalves
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Patent number: 8426213Abstract: The present invention relates to providing improved hydrogen peroxide assays, as well as droplet actuators for conducting such assays. The droplet actuators of the invention may be used to conduct droplet-based hydrogen peroxide assays. They may also be associated with detectors for analyzing the results of the hydrogen peroxide assays of the invention. They may be provided as components of systems which control droplet operations and/or detection for conducting the hydrogen peroxide assays. Measurement by the detector may be used to quantify the presence of an analyte in a sample.Type: GrantFiled: March 5, 2008Date of Patent: April 23, 2013Assignee: Advanced Liquid Logic IncInventors: Allen E. Eckhardt, Vijay Srinivasan, Vamsee K. Pamula
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Patent number: 8415166Abstract: The present invention provides a device for the detection of a peroxide-based explosive, in particular, triacetone triperoxide (TATP), which is based on a molecular controlled semiconductor resistor (MOCSER) and composed of at least one insulating or semi-insulating layer, at least one conducting semiconductor layer, two conducting pads and a layer of multifunctional organic molecules capable of adsorbing molecules of the peroxide-based explosive. The invention further provides an array of semiconductor devices for the selective detection of a peroxide-based explosive, as well as a method for the selective detection of vapors of a peroxide-based explosive in a gaseous mixture using this array.Type: GrantFiled: May 12, 2009Date of Patent: April 9, 2013Assignee: Yeda Research and Development Co. Ltd.Inventors: Ron Naaman, Eyal Capua, Roberto Cao
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Publication number: 20130034911Abstract: A system for a vehicle includes a first ozone sensor that generates a first sensor signal indicating a first amount of ozone in air flowing into a radiator. A second ozone sensor generates a second sensor signal indicating a second amount of ozone in air flowing out of the radiator. A control module receives the first sensor signal and the second sensor signal and determines an ozone conversion rate based on the first sensor signal and the second sensor signal.Type: ApplicationFiled: November 8, 2011Publication date: February 7, 2013Applicant: GM Global Technology Operations LLCInventors: Scott H. Wittkopp, Chang H. Kim, Brian T. Heil
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Patent number: 8361802Abstract: A selective, fluorescent “turn-on” probe and method for the detection of ozone in biological and atmospheric samples, wherein the method of detecting ozone in a sample comprises the steps of (1) contacting the sample with a fluorophore capable of undergoing allylic ether or allylic ester cleavage and (2) detecting fluorescence in the sample.Type: GrantFiled: March 9, 2010Date of Patent: January 29, 2013Assignee: University of Pittsburgh—Of the Commonwealth System of Higher EducationInventors: Kazunori Koide, Amanda L. Garner
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Publication number: 20120315659Abstract: A colorimetric reagent in the form of nanoparticles, composite nanoparticles, and nanoparticle coatings, including methods of use, methods of preparation, deposition, and assembly of related devices and specific applications. The colorimetric reagent comprises cerium oxide nanoparticles which are used in solution or immobilized on a solid support, either alone or in conjunction with oxidase enzymes, to form an active colorimetric component that reacts with an analyte to form a colored complex. The rate of color change and the intensity of the color are proportional to the amount of analyte present in the sample. Also described is the use of ceria and doped ceria nanoparticles as an oxygen storage/delivery vehicle for oxidase enzymes and applications in biocatalytic processes in anaerobic conditions of interest in biomedicine and bioanalysis.Type: ApplicationFiled: June 9, 2011Publication date: December 13, 2012Applicant: Clarkson UniversityInventors: Emanuela Silvana Andreescu, Maryna Ornatska, Cristina R. Ispas, Daniel Andreescu
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Publication number: 20120309047Abstract: A sensor system, and a method of detecting a target analyte, comprises a chemically functionalized block copolymer, and a target analyte. The block copolymer exhibits a color change in the visible spectrum upon exposure to the target analyte.Type: ApplicationFiled: May 31, 2012Publication date: December 6, 2012Applicant: University of Maryland, College ParkInventors: Peter Kofinas, Omar B. Ayyub, Jennifer W. Sekowski, Ta-I Yang
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Patent number: 8304251Abstract: Systems and methods are disclosed to automatically detect the presence of a substance on a test swipe by capturing a background image of the test swipe; applying one or more test chemicals to a test swipe; adjusting the temperature of the test swipe to a predetermined temperature range; capturing an in-situ image of the test swipe after the application of chemical at the predetermined temperature range; subtracting the background image from the in-situ image; generating a difference value from the two images; and searching a known database to identify the substance.Type: GrantFiled: February 18, 2009Date of Patent: November 6, 2012Assignee: Chem Spectra, Inc.Inventors: Jeffrey Haas, Douglas Haas
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Publication number: 20120276651Abstract: The present disclosure relates to a sulfonated benzene compound emitting fluorescence by reaction with hydrogen peroxide, aqueous-dispersed fluorescent nanoprobes applicable for real-time detection of hydrogen peroxide, and a fluorescent nanoprobe fabrication method. The fluorescent nanoprobe contains the following sulfonated benzene compound and water.Type: ApplicationFiled: January 31, 2012Publication date: November 1, 2012Applicant: KOREA INSTITUTE OF SCIENCE AND TECHNOLOGYInventors: Sehoon KIM, Ick Chan Kwon, Jai Kyeong Kim, Chang-Keun Lim, Jeongyun Heo
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Patent number: 8288163Abstract: The present invention relates to a device and process for the quick and reliable online detection of triacetone triperoxide (TATP).Type: GrantFiled: February 11, 2009Date of Patent: October 16, 2012Assignees: Rheinische Friedrich-Wilhelms-Universitaet Bonn, Max-Planck-Gesellschaft zur Foerderung der Wissenschaften E.V.Inventors: Siegfried R. Waldvogel, Jürgen Lörgen, Daniel Lubczyk, Klaus Müllen, Roland Bauer
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Patent number: 8288164Abstract: The present invention provides a highly reliable reaction cuvette in which air bubbles are adhered little and mutual contamination can be prevented among samples and reagents in adjoining reaction cuvettes, a method of surface treatment for a reaction cuvette, and an automatic analyzer with the reaction cuvette mounted therein. The reaction cuvette according to the present invention, in which a sample and a reagent are mixed with each other and its concentration is measured, has an area subjected to hydrophilic treatment by electric discharging on inner and outer surfaces of the reaction cuvette. Further the reaction cuvette has a container-like form with its upper portion opened to provide an opening and its lower portion closed to provide a bottom. The hydrophilic area is present from a bottom of the reaction cuvette up to a midway to the opening.Type: GrantFiled: May 14, 2008Date of Patent: October 16, 2012Assignee: Hitachi High-Technologies CorporationInventors: Hiroyuki Mishima, Hiroaki Ishizawa, Masashi Endo
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Publication number: 20120183984Abstract: The invention provides compounds of formula I F-L-Q (I) where F comprises a fluorophore capable of absorbing energy at an excitation wavelength and, in the absence of a quencher, emitting energy at an emission wavelength, which is different than the excitation wavelength; Q comprises a quencher; L comprises a linker moiety having two ends, one end being covalently bound to F and the other end being covalently bound to Q. The compounds are capable of undergoing a reversible reaction (1), provided below: (1) where Q+ is an oxidized form of Q representing the absence of a quencher, Ox comprises an oxidizing agent, which is capable of oxidizing Q to its oxidized form Q, and Red comprises a reducing agent, which is capable of converting Q back to its reduced form Q. The compounds can undergo photo-induced electron transfer when irradiated with energy and when Q exists in its oxidized form, Q+.Type: ApplicationFiled: July 22, 2010Publication date: July 19, 2012Applicant: OPTI MEDICAL SYSTEMSInventors: Huarui He, Chao Lin
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Publication number: 20120149601Abstract: Methods, systems and related apparatus for fluorescence-based detection of various nitro and peroxide compounds.Type: ApplicationFiled: March 21, 2008Publication date: June 14, 2012Inventors: Michael J. Knapp, Meaghan Germain
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Patent number: 8183049Abstract: With respect to a lead detection method that uses rhodizonic acid, it is made possible to clearly identify pink or red coloration caused by a reaction between lead and rhodizonic acid even in cases where Sn is present in a specimen. To this end, an acidic aqueous solution or a buffer solution thereof (e.g., tartaric acid) in which hydrogen peroxide coexists is used as a reagent. Hydrogen peroxide oxidizes Sn2+ into Sn4+. Since Sn4+ does not react with rhodizonic acid, the presence of Sn does not interfere with the visual identification of any pink or red coloration caused by the reaction between lead and rhodizonic acid.Type: GrantFiled: October 30, 2008Date of Patent: May 22, 2012Assignee: Toyota Jidosha Kabushiki KaishaInventors: Kengo Kayano, Naoki Sato, Shinichiro Hirayama
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Patent number: 8178357Abstract: Sensors, sensing systems and sensing methods of the invention provide for detection of peroxides, including for example, vapor-phase H2O2 and organic peroxides such as di-tert-butyl peroxide. A sensor and sensing method of the invention uses at least two phthalocyanines, one of which exhibits an oxidation reaction with peroxides and the other of which exhibits a reduction reaction with peroxides. A peroxide is readily identified by a sensor of the invention when one of the at least two phthalocyanines exhibits increased resistance to current flow and the other of the at least two phthalocyanines exhibits decreased resistance to current flow.Type: GrantFiled: July 23, 2008Date of Patent: May 15, 2012Assignee: The Regents of the University of CaliforniaInventors: William C. Trogler, Forest Bohrer, Andrew C. Kummel